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ea0022p159 | Cardiovascular endocrinology and lipid metabolism | ECE2010

Changes in serum concentrations and tissue expression of fibroblast growth factor-21 during and after elective major cardiac surgery

Drapalova Jana , Kotulak Tomas , Kopecky Petr , Mraz Milos , Riha Hynek , Blaha Jan , Kramar Petr , Netuka Ivan , Maly Jan , Kremen Jaromir , Kotrlikova Eva , Svacina Stepan , Haluzik Martin

Introduction: Fibroblast growth factor-21 (FGF-21) is a novel regulator of glucose and lipid metabolism and insulin sensitivity. Possible role of FGF-21 in the development of insulin resistance in critically ill patients has not been studied yet.Objective: To study the changes in FGF21 production and adipose tissue and skeletal muscle FGF-21 mRNA gene expression in cardiac surgery patients.Methods: Sixteen patients (16 men, aged 66...
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Endocrine Abstracts
ISSN 1470-3947 (print) | ISSN 1479-6848 (online)
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